Pepti · Catalog · PE-22-28

TREK-1 channel research · research-use

PE-22-28 OEM supply.

Spadin-derived heptapeptide (mini-spadin) and selective TREK-1 potassium-channel inhibitor, manufactured with per-lot COA, HPLC, and MS documentation for research and private-label programs.

PE-22-28 lyophilized vial
PE-22-28HPLC ≥ 99%MS confirmed5mg / 10mg

Vial illustrations reflect supplied lyophilized format. Distribution scope and destination market confirmed before invoicing.

CompoundPE-22-28
CAS number1801959-12-5
Molecular formulaC35H55N11O9
Molecular weight773.9 g/mol
SequenceGly-Val-Ser-Trp-Gly-Leu-Arg (GVSWGLR)
FormLyophilized powder, glass vial
Purity target≥ 99% by HPLC
Vial formats5mg / 10mg
DocumentationBatch-linked COA + HPLC chromatogram + MS identity record for every production lot
Distribution scopeResearch use, worldwide
StorageStore lyophilized powder at -20°C, protected from light and moisture; stable long-term when sealed. After reconstitution, keep at 2-8°C and use within a short period. Avoid repeated freeze-thaw cycles.

MOQ & lead time

TierQuantityLead time
OEM lot50 kits (500 vials)3–7 days
Production lot500–1,000 vials10–14 days
OEM repeat1,000+ vials14–18 days, scheduled

Supplied as a research-use peptide. Every quote confirms current-batch COA, purity, destination market and buyer track before invoicing.

Overview

About PE-22-28.

PE-22-28 is a seven-residue peptide corresponding to residues 22-28 of spadin, the endogenous sortilin-derived peptide, and is often called "mini-spadin." It acts as a selective blocker of the TREK-1 (TWIK-related potassium) channel, a two-pore-domain K+ channel studied as a target in neurogenesis, synaptic-signaling, and mood-related preclinical research.

Documentation

Batch documentation support for PE-22-28 lots.

batch-linked COA, HPLC chromatogram and MS identity record for every production lot. Distribution scope confirmed before invoicing.

HPLC purity

Reverse-phase HPLC with UV detection; purity target reported per lot with related-substance reporting on request.

MS identity

Mass spectrometry identity confirmation against the PE-22-28 reference profile.

Lot traceability

Compound prefix and lot serial printed on the vial label and repeated in the document pack and carton.

FAQ

PE-22-28 — frequently asked by B2B buyers.

What exactly is PE-22-28?

PE-22-28 is a synthetic heptapeptide (sequence GVSWGLR) corresponding to residues 22-28 of spadin, a sortilin-derived peptide, and is sometimes called mini-spadin. In preclinical research it is characterized as a selective TREK-1 potassium-channel inhibitor. All material is supplied strictly for laboratory and research use.

What purity and documentation do you provide?

Every production lot includes a batch-linked COA including RP-HPLC purity target (≥99%; actual result shown in lot documents) and mass-spectrometry identity confirmation matching the C35H55N11O9 / ~773.9 g/mol profile. Additional data such as residual-solvent, water-content, or endotoxin (only if specifically ordered and tested) testing can be provided on request for OEM programs.

What vial size and MOQ are available?

Standard catalog formats are 5 mg and 10 mg lyophilized vials, with a minimum order of 50 kits (500 vials).

Can you private-label or customize PE-22-28?

Yes. We support OEM and private-label programs including custom vial fill, labeling, and packaging. Analogs and sequence modifications built on the GVSWGLR core can be scoped on RFQ, subject to feasibility review.

How is PE-22-28 shipped and handled for compliance?

Lyophilized material ships with documentation identifying it as a research-use-only chemical, not for consumer or veterinary use. Cold-chain or ambient shipping is selected by destination and transit time, and export paperwork is prepared per the buyer's jurisdiction.

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