HPLC purity
Reverse-phase HPLC with UV detection; purity target reported per lot with related-substance reporting on request.
Vial illustrations reflect supplied lyophilized format. Distribution scope and destination market confirmed before invoicing.
| Compound | PE-22-28 |
|---|---|
| CAS number | 1801959-12-5 |
| Molecular formula | C35H55N11O9 |
| Molecular weight | 773.9 g/mol |
| Sequence | Gly-Val-Ser-Trp-Gly-Leu-Arg (GVSWGLR) |
| Form | Lyophilized powder, glass vial |
| Purity target | ≥ 99% by HPLC |
| Vial formats | 5mg / 10mg |
| Documentation | Batch-linked COA + HPLC chromatogram + MS identity record for every production lot |
| Distribution scope | Research use, worldwide |
| Storage | Store lyophilized powder at -20°C, protected from light and moisture; stable long-term when sealed. After reconstitution, keep at 2-8°C and use within a short period. Avoid repeated freeze-thaw cycles. |
| Tier | Quantity | Lead time |
|---|---|---|
| OEM lot | 50 kits (500 vials) | 3–7 days |
| Production lot | 500–1,000 vials | 10–14 days |
| OEM repeat | 1,000+ vials | 14–18 days, scheduled |
Supplied as a research-use peptide. Every quote confirms current-batch COA, purity, destination market and buyer track before invoicing.
Overview
PE-22-28 is a seven-residue peptide corresponding to residues 22-28 of spadin, the endogenous sortilin-derived peptide, and is often called "mini-spadin." It acts as a selective blocker of the TREK-1 (TWIK-related potassium) channel, a two-pore-domain K+ channel studied as a target in neurogenesis, synaptic-signaling, and mood-related preclinical research.
Documentation
batch-linked COA, HPLC chromatogram and MS identity record for every production lot. Distribution scope confirmed before invoicing.
Reverse-phase HPLC with UV detection; purity target reported per lot with related-substance reporting on request.
Mass spectrometry identity confirmation against the PE-22-28 reference profile.
Compound prefix and lot serial printed on the vial label and repeated in the document pack and carton.
FAQ
PE-22-28 is a synthetic heptapeptide (sequence GVSWGLR) corresponding to residues 22-28 of spadin, a sortilin-derived peptide, and is sometimes called mini-spadin. In preclinical research it is characterized as a selective TREK-1 potassium-channel inhibitor. All material is supplied strictly for laboratory and research use.
Every production lot includes a batch-linked COA including RP-HPLC purity target (≥99%; actual result shown in lot documents) and mass-spectrometry identity confirmation matching the C35H55N11O9 / ~773.9 g/mol profile. Additional data such as residual-solvent, water-content, or endotoxin (only if specifically ordered and tested) testing can be provided on request for OEM programs.
Standard catalog formats are 5 mg and 10 mg lyophilized vials, with a minimum order of 50 kits (500 vials).
Yes. We support OEM and private-label programs including custom vial fill, labeling, and packaging. Analogs and sequence modifications built on the GVSWGLR core can be scoped on RFQ, subject to feasibility review.
Lyophilized material ships with documentation identifying it as a research-use-only chemical, not for consumer or veterinary use. Cold-chain or ambient shipping is selected by destination and transit time, and export paperwork is prepared per the buyer's jurisdiction.
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