HPLC purity
Reverse-phase HPLC with UV detection; purity target reported per lot with related-substance reporting on request.
Vial illustrations reflect supplied lyophilized format. Distribution scope and destination market confirmed before invoicing.
| Compound | FOXO4-DRI |
|---|---|
| CAS number | 2460055-10-9 |
| Molecular formula | C228H388N86O64 |
| Molecular weight | 5358.15 g/mol (free base) |
| Sequence | LTLRKEPASEIAQSILEAYSQNGWANRRSGGKRPPPRRRQRRKKRG (46 residues, all-D retro-inverso) |
| Form | Lyophilized powder, glass vial |
| Purity target | ≥ 99% by HPLC |
| Vial formats | 2mg / 10mg |
| Documentation | Batch-linked COA + HPLC chromatogram + MS identity record for every production lot |
| Distribution scope | Research use, worldwide |
| Storage | Store lyophilized powder at -20 °C; ship on cold packs. After reconstitution keep at 2-8 °C and use within the validated window. Protect from light and avoid repeated freeze-thaw cycles. |
| Tier | Quantity | Lead time |
|---|---|---|
| OEM lot | 50 kits (500 vials) | 3–7 days |
| Production lot | 500–1,000 vials | 10–14 days |
| OEM repeat | 1,000+ vials | 14–18 days, scheduled |
Supplied as a research-use peptide. Every quote confirms current-batch COA, purity, destination market and buyer track before invoicing.
Overview
FOXO4-DRI is a cell-penetrating D-retro-inverso peptide built from a FOXO4 p53-binding fragment fused to a TAT-derived import sequence, placing it in the senolytic / cellular-aging research class. In published cell and animal studies it competes with endogenous FOXO4 for p53, releasing p53 to induce apoptosis preferentially in senescent cells.
Documentation
batch-linked COA, HPLC chromatogram and MS identity record for every production lot. Distribution scope confirmed before invoicing.
Reverse-phase HPLC with UV detection; purity target reported per lot with related-substance reporting on request.
Mass spectrometry identity confirmation against the FOXO4-DRI reference profile.
Compound prefix and lot serial printed on the vial label and repeated in the document pack and carton.
FAQ
FOXO4-DRI is stocked as lyophilized powder in 2 mg and 10 mg vials, with a minimum order of 50 kits (500 vials). Larger bulk quantities and custom fills are quoted on RFQ.
Every lot ships with a batch-specific certificate of analysis showing HPLC purity and mass-spec (MS) identity confirmation. Additional COA parameters and third-party testing can be arranged on request.
Yes. FOXO4-DRI is synthesized as an all-D-amino-acid retro-inverso construct — the residue order is reversed and built from D-amino acids — which is characteristic of this molecule and improves proteolytic stability versus a native L-peptide.
Yes. We supply bulk peptide and support private-label filling, custom vial sizing, and label/packaging for research-use brands. Regulatory positioning and compliance in the buyer's market remain the buyer's responsibility.
FOXO4-DRI is typically supplied with a ≥99% HPLC purity target. Actual purity, net-peptide content, endotoxin (only if specifically ordered and tested), and residual-solvent specifications are confirmed per lot on the COA and can be tailored on RFQ.
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